National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

KRAS Gene
Synonyms

KRas Proto-Oncogene, GTPase Gene

K-ras gene

KRAS

KRAS Gene

Kras gene
Definitions

This gene is involved in signal transduction and apoptosis.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25785
ALT_DEFINITION

A gene that may cause cancer when it is mutated (changed). The Kras gene makes the KRAS protein, which is involved in cell signaling pathways, cell growth, and apoptosis (cell death). Agents that block the activity of the mutated Kras gene or its protein may stop the growth of cancer.
code

C25785
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177281

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177517

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142801
Contributing_Source

CCPS

CTRP

GDC
DEFINITION

This gene is involved in signal transduction and apoptosis.
Display_Name

KRAS Gene
FULL_SYN

KRas Proto-Oncogene, GTPase Gene

K-ras gene

KRAS

KRAS Gene

Kras gene
HGNC_ID

HGNC:6407
Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173595

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171253
label

KRAS Gene
Legacy Concept Name

KRAS2_Gene
Maps_To

KRAS
OMIM_Number

190070
Preferred_Name

KRAS Gene
prefixIRI

Thesaurus:C25785
Semantic_Type

Gene or Genome
UMLS_CUI

C1537502
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25784
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