National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Podophyllin
Synonyms

Podophyllin

PODOPHYLLUM RESIN

Mayapple Extract

Podophyllin Resin

Definitions

A resin extracted from the root of the plant Podophyllum sp. Berberidaceae (mandrake), which contains numerous compounds, among which podophyllotoxin is the principal active component. Podophyllin arrests mitosis in metaphase. Podophyllotoxin offers advantages over podophyllin in terms of purity, stability and lack of systemic toxicity. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2362

CAS_Registry

9000-55-9

code

C2362

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A resin extracted from the root of the plant Podophyllum sp. Berberidaceae (mandrake), which contains numerous compounds, among which podophyllotoxin is the principal active component. Podophyllin arrests mitosis in metaphase. Podophyllotoxin offers advantages over podophyllin in terms of purity, stability and lack of systemic toxicity. (NCI04)

FDA_UNII_Code

16902YVY2B

FULL_SYN

Podophyllin

PODOPHYLLUM RESIN

Mayapple Extract

Podophyllin Resin

label

Podophyllin

Legacy Concept Name

Podophyllin

NSC Number

36390

Preferred_Name

Podophyllin

prefixIRI

Thesaurus:C2362

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0032333

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1331

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