loading...| Preferred Name |
Interferon Alfa-N1 |
|
| Synonyms |
Interferon Alfa-N1 Interferon alfa-n1 INTERFERON ALFA-N1 Interferon Alfa Humoferon Wellferon |
|
| Definitions |
A highly purified alpha interferon produced by a human lymphoid cell line. Interferon alpha-n1 consists of multiple alpha interferon subtypes, at least two of which are glycosylated. In contrast, recombinant alpha interferons are individual non-glycosylated proteins produced from individual alpha interferon genes. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose proteins have antiviral, antiproliferative, anticancer, and immune-modulating effects. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2220 |
|
| Accepted_Therapeutic_Use_For |
Chronic Hepatitis C |
|
| CAS_Registry |
308067-63-2 |
|
| code |
C2220 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
FDA GDC HemOnc |
|
| DEFINITION |
A highly purified alpha interferon produced by a human lymphoid cell line. Interferon alpha-n1 consists of multiple alpha interferon subtypes, at least two of which are glycosylated. In contrast, recombinant alpha interferons are individual non-glycosylated proteins produced from individual alpha interferon genes. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose proteins have antiviral, antiproliferative, anticancer, and immune-modulating effects. (NCI04) |
|
| FDA_UNII_Code |
41697D4Z5C |
|
| FULL_SYN |
Interferon Alfa-N1 Interferon alfa-n1 INTERFERON ALFA-N1 Interferon Alfa Humoferon Wellferon |
|
| Is_Value_For_GDC_Property | ||
| label |
Interferon Alfa-N1 |
|
| Legacy Concept Name |
Interferon_Alfa-N1 |
|
| Maps_To |
Interferon Alfa-N1 |
|
| Preferred_Name |
Interferon Alfa-N1 |
|
| prefixIRI |
Thesaurus:C2220 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance |
|
| UMLS_CUI |
C0699817 |
|
| subClassOf |