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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Fibroblast Growth Factor 1 | |
| Synonyms |
Beta-Endothelial Cell Growth Factor Prostatropin Heparin Binding Growth Factor 1 Endothelial Cell Growth Factor, Beta Endothelial Cell Growth Factor, Alpha Endothelial Cell Growth Factor Acidic Fibroblast Growth Factor Heparin Binding Growth Factor-1 Fibroblast Growth Factor 1 Alpha Fibroblast Growth Factor ECGF FGF-1 FGF1 HBGF-1 aFGF |
|
| Definitions |
Fibroblast growth factor 1 (17 aa, ~155 kDa) is encoded by the human FGF1 gene. This protein plays a role in cell proliferation, angiogenesis, cell differentiation, and cell migration. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20548 |
|
| code |
C20548
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP
|
|
| DEFINITION |
Fibroblast growth factor 1 (17 aa, ~155 kDa) is encoded by the human FGF1 gene. This protein plays a role in cell proliferation, angiogenesis, cell differentiation, and cell migration.
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|
| DesignNote |
Fibroblast growth factor 1 lacks a cleavable signal sequence; it is transported through the cytoplasm to the cell membrane and then secreted by a non-classical pathway that requires Cu2+ ions and protein S100-A13. (UniProt)
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|
| Display_Name |
Fibroblast Growth Factor 1
|
|
| FULL_SYN |
Beta-Endothelial Cell Growth Factor Prostatropin Heparin Binding Growth Factor 1 Endothelial Cell Growth Factor, Beta Endothelial Cell Growth Factor, Alpha Endothelial Cell Growth Factor Acidic Fibroblast Growth Factor Heparin Binding Growth Factor-1 Fibroblast Growth Factor 1 Alpha Fibroblast Growth Factor ECGF FGF-1 FGF1 HBGF-1 aFGF
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|
| label |
Fibroblast Growth Factor 1
|
|
| Legacy Concept Name |
Fibroblast_Growth_Factor-1
|
|
| OMIM_Number |
131220
|
|
| Preferred_Name |
Fibroblast Growth Factor 1
|
|
| prefixIRI |
Thesaurus:C20548
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|
| Semantic_Type |
Amino Acid, Peptide, or Protein
|
|
| Swiss_Prot |
P05230
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|
| UMLS_CUI |
C0079349
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|
| subClassOf |
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