National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Fibroblast Growth Factor

Synonyms

DNA Synthesis Factor

Fibroblast Growth Factor

Fibroblast Growth Regulatory Factor

Endothelial Cell Growth Factor

Fibroblast Growth Factor Family

ECGF

FGF

FGF Family

Definitions

A family of structurally-related growth factors with high affinity for heparin. These proteins modulate cell proliferation, angiogenesis, wound healing, embryogenesis and paracrine signaling pathways. Fibroblast growth factors (FGF) stimulate signal transduction through binding to specific members of the fibroblast growth factor receptors (FGFR) family tyrosine kinases.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20426

code

C20426

DEFINITION

A family of structurally-related growth factors with high affinity for heparin. These proteins modulate cell proliferation, angiogenesis, wound healing, embryogenesis and paracrine signaling pathways. Fibroblast growth factors (FGF) stimulate signal transduction through binding to specific members of the fibroblast growth factor receptors (FGFR) family tyrosine kinases.

FULL_SYN

DNA Synthesis Factor

Fibroblast Growth Factor

Fibroblast Growth Regulatory Factor

Endothelial Cell Growth Factor

Fibroblast Growth Factor Family

ECGF

FGF

FGF Family

label

Fibroblast Growth Factor

Legacy Concept Name

Fibroblast_Growth_Factor

Preferred_Name

Fibroblast Growth Factor

prefixIRI

Thesaurus:C20426

Semantic_Type

Amino Acid, Peptide, or Protein

Biologically Active Substance

UMLS_CUI

C0016026

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20424

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