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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Brain-Derived Neurotrophic Factor | |
| Synonyms |
Brain-Derived Neurotrophic Factor Brain Derived Neurotrophic Factor Abrineurin BDNF |
|
| Definitions |
Brain-derived neurotrophic factor (247 aa, ~28 kDa) is encoded by the human BDNF gene. This protein plays a role in both the development of the nervous system and neuronal survival. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20445 |
|
| code |
C20445
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP
|
|
| DEFINITION |
Brain-derived neurotrophic factor (247 aa, ~28 kDa) is encoded by the human BDNF gene. This protein plays a role in both the development of the nervous system and neuronal survival.
|
|
| DesignNote |
The active form of brain-derived neurotrophic factor is produced by proteolytic cleaves that remove 128 N-terminal residues from the full length precursor protein. (UniProt)
|
|
| Display_Name |
Brain-Derived Neurotrophic Factor
|
|
| FULL_SYN |
Brain-Derived Neurotrophic Factor Brain Derived Neurotrophic Factor Abrineurin BDNF
|
|
| label |
Brain-Derived Neurotrophic Factor
|
|
| Legacy Concept Name |
Brain-Derived_Neurotrophic_Factor
|
|
| OMIM_Number |
113505
|
|
| Preferred_Name |
Brain-Derived Neurotrophic Factor
|
|
| prefixIRI |
Thesaurus:C20445
|
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
|
|
| Swiss_Prot |
P23560
|
|
| UMLS_CUI |
C3486709
|
|
| subClassOf |
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