National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Neurotrophic Factor
Synonyms

Neurotrophin

Neurotrophic Factor

Definitions

A family of protein growth factors produced by the nervous system and peripheral target tissues. These proteins are critical for development, growth, regeneration, survival, and differentiation of neurons.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20391

code

C20391

DEFINITION

A family of protein growth factors produced by the nervous system and peripheral target tissues. These proteins are critical for development, growth, regeneration, survival, and differentiation of neurons.

DesignNote

Neurotrophin signaling is mediated by the Trk family of receptor tyrosine kinases. (IP, N. Y. (1998), The Neurotrophins and Neuropoietic Cytokines: Two Families of Growth Factors Acting on Neural and Hematopoietic Cells. Annals of the New York Academy of Sciences, 840: 97-106. doi: 10.1111/j.1749-6632.1998.tb09553.x)

FULL_SYN

Neurotrophin

Neurotrophic Factor

label

Neurotrophic Factor

Legacy Concept Name

Neurotrophic_Factor

Preferred_Name

Neurotrophic Factor

prefixIRI

Thesaurus:C20391

Semantic_Type

Amino Acid, Peptide, or Protein

Biologically Active Substance

UMLS_CUI

C0132298

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20424

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