National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Monoclonal Antibody
Synonyms

monoclonal antibody

Monoclonal Antibody Therapy

Monoclonal Antibodies

Monoclonal Antibody

MAb

MoAB

Definitions

An antibody produced by a clone or genetically homogenous fast-growing cells i.e., hybridoma. Hybridoma cells are cloned to establish cell lines producing a specific antibody that is chemically and immunologically homogeneous. They are widely used in cancer detection, diagnosis, and treatment.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20401

ALT_DEFINITION

A type of protein made in the laboratory that can bind to substances in the body, including tumor cells. There are many kinds of monoclonal antibodies. Each monoclonal antibody is made to find one substance. Monoclonal antibodies are being used to treat some types of cancer and are being studied in the treatment of other types. They can be used alone or to carry drugs, toxins, or radioactive materials directly to a tumor.

code

C20401

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

An antibody produced by a clone or genetically homogenous fast-growing cells i.e., hybridoma. Hybridoma cells are cloned to establish cell lines producing a specific antibody that is chemically and immunologically homogeneous. They are widely used in cancer detection, diagnosis, and treatment.

Display_Name

Monoclonal Antibody

FULL_SYN

monoclonal antibody

Monoclonal Antibody Therapy

Monoclonal Antibodies

Monoclonal Antibody

MAb

MoAB

label

Monoclonal Antibody

Legacy Concept Name

Monoclonal_Antibody

Preferred_Name

Monoclonal Antibody

prefixIRI

Thesaurus:C20401

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0003250

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C308

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C307

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