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National Cancer Institute Thesaurus
| Preferred Name | Recombinant Interferon Alfa-2b | |
| Synonyms |
Interferon alfa 2b interferon alfa-2b IFN alpha-2B Interferon Alfa-2B Interferon Alpha-2b Heberon Alfa Recombinant Interferon Alfa-2b recombinant interferon alfa-2b INTERFERON ALFA-2B Interferon alfa-2b Alfatronol Glucoferon Intron A Sch 30500 Urifron Viraferon |
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| Definitions |
A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1953 |
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| ALT_DEFINITION |
A drug used to treat some infections caused by viruses and several types of cancer. These include hairy cell leukemia, melanoma, and follicular lymphoma. It is a form of interferon alfa (a substance normally made by cells of the immune system) that is made in the laboratory. It is a type of biological response modifier.
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| CAS_Registry |
98530-12-2 99210-65-8
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|
| code |
C1953
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
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| Contributing_Source |
CTRP FDA GDC HemOnc
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|
| DEFINITION |
A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects.
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| Display_Name |
Recombinant Interferon Alfa-2b
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| FDA_UNII_Code |
43K1W2T1M6
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| FULL_SYN |
Interferon alfa 2b interferon alfa-2b IFN alpha-2B Interferon Alfa-2B Interferon Alpha-2b Heberon Alfa Recombinant Interferon Alfa-2b recombinant interferon alfa-2b INTERFERON ALFA-2B Interferon alfa-2b Alfatronol Glucoferon Intron A Sch 30500 Urifron Viraferon
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| Has_Target | ||
| Is_Value_For_GDC_Property | ||
| label |
Recombinant Interferon Alfa-2b
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|
| Legacy Concept Name |
Recombinant_Interferon_Alfa-2b
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|
| Maps_To |
Recombinant Interferon Alfa-2b
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| NCI_Drug_Dictionary_ID |
462279
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| NSC Number |
377523
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| PDQ_Closed_Trial_Search_ID |
462279
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| PDQ_Open_Trial_Search_ID |
462279
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|
| Preferred_Name |
Recombinant Interferon Alfa-2b
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|
| prefixIRI |
Thesaurus:C1953
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| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance
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| UMLS_CUI |
C0021735
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
| Mapping To | Ontology | Source |
|---|---|---|
| http://purl.obolibrary.org/obo/NCIT_C1953 | BERO | LOOM |
| http://purl.bioontology.org/ontology/PDQ/CDR0000462279 | PDQ | LOOM |