National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

ATP-Binding Cassette Sub-Family C Member 8
Synonyms

ATP Binding Cassette Subfamily C Member 8

ATP-Binding Cassette Transporter Sub-Family C Member 8

Sulfonylurea Receptor 1

ATP-Binding Cassette Sub-Family C Member 8

ABCC8

SUR

SUR1

Definitions

ATP-binding cassette sub-family C member 8 (1581 aa, ~177 kDa) is encoded by the human ABCC8 gene. This protein is involved in ATPase-coupled transmembrane transport of potassium ions and insulin.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191885

code

C191885

DEFINITION

ATP-binding cassette sub-family C member 8 (1581 aa, ~177 kDa) is encoded by the human ABCC8 gene. This protein is involved in ATPase-coupled transmembrane transport of potassium ions and insulin.

DesignNote

ATP-binding cassette sub-family C member 8 is expressed in pancreatic beta-cell and is the target for sulfonylurea-based antidiabetic therapeutics.

FULL_SYN

ATP Binding Cassette Subfamily C Member 8

ATP-Binding Cassette Transporter Sub-Family C Member 8

Sulfonylurea Receptor 1

ATP-Binding Cassette Sub-Family C Member 8

ABCC8

SUR

SUR1

label

ATP-Binding Cassette Sub-Family C Member 8

NCI_META_CUI

CL359373

OMIM_Number

600509

Preferred_Name

ATP-Binding Cassette Sub-Family C Member 8

prefixIRI

Thesaurus:C191885

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

Q09428

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17750

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