National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

ABC Transporter
Synonyms

ATP Binding Cassette Transporter

ABC Transporter Protein

ATP-Binding Cassette Transporter

ABC Transporter

ABC Transport Protein

Definitions

A family of transmembrane proteins that usually function as dimers to hydrolyze ATP, which permits them to transport a wide variety of substrates across cellular membranes. These proteins consist of two distinct domains, a transmembrane domain and a nucleotide-binding domain. ATP binding is required for both dimerization and transporter activity.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17750

code

C17750

DEFINITION

A family of transmembrane proteins that usually function as dimers to hydrolyze ATP, which permits them to transport a wide variety of substrates across cellular membranes. These proteins consist of two distinct domains, a transmembrane domain and a nucleotide-binding domain. ATP binding is required for both dimerization and transporter activity.

FULL_SYN

ATP Binding Cassette Transporter

ABC Transporter Protein

ATP-Binding Cassette Transporter

ABC Transporter

ABC Transport Protein

label

ABC Transporter

Legacy Concept Name

ABC_Transporter

Preferred_Name

ABC Transporter

prefixIRI

Thesaurus:C17750

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0242738

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16386

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