loading...| Preferred Name |
Cathepsin B |
|
| Synonyms |
APP Secretase Cathepsin B Cathepsin B1 Amyloid Precursor Protein Secretase EC 3.4.22.1 Preprocathepsin B APPS CTSB |
|
| Definitions |
Cathepsin B (339 aa, ~38 kDa) is encoded by the human CTSB gene. This protein plays a role in proteolysis, immunity and the regulation of apoptosis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18267 |
|
| code |
C18267 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP |
|
| DEFINITION |
Cathepsin B (339 aa, ~38 kDa) is encoded by the human CTSB gene. This protein plays a role in proteolysis, immunity and the regulation of apoptosis. |
|
| DesignNote |
Cathepsin B is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). (Entrez Gene) Cathepsin B is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. |
|
| Display_Name |
Cathepsin B |
|
| FULL_SYN |
APP Secretase Cathepsin B Cathepsin B1 Amyloid Precursor Protein Secretase EC 3.4.22.1 Preprocathepsin B APPS CTSB |
|
| label |
Cathepsin B |
|
| Legacy Concept Name |
Cathepsin-B |
|
| OMIM_Number |
116810 |
|
| Preferred_Name |
Cathepsin B |
|
| prefixIRI |
Thesaurus:C18267 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme |
|
| Swiss_Prot |
P07858 |
|
| UMLS_CUI |
C2606206 |
|
| subClassOf |