Preferred Name | Gel Electrophoresis | |
Synonyms |
GEL ELECTROPHORESIS Gel Electrophoresis Gel Electropheresis |
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Definitions |
Gel electrophoresis is a method of separating large molecules (such as DNA fragments or proteins) from a mixture of similar molecules by electrophoretic filtration through a gelatinous matrix. Subject to an electric field, each molecule in the sample mixture migrates through the matrix at a different rate, depending mainly on electrical charge and size, resulting in spatial separation within the matrix of each molecular species in the sample mixture. Agarose and acrylamide in a cylindrical tube or slab gel are commonly used media for electrophoresis of proteins and nucleic acids. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18091 |
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ALT_DEFINITION |
A method of separating large molecules (such as DNA fragments or proteins) from a mixture of similar molecules by electrophoretic filtration through a gelatinous matrix. |
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code |
C18091 |
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Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173233 |
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Contributing_Source |
CDISC PCDC |
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DEFINITION |
Gel electrophoresis is a method of separating large molecules (such as DNA fragments or proteins) from a mixture of similar molecules by electrophoretic filtration through a gelatinous matrix. Subject to an electric field, each molecule in the sample mixture migrates through the matrix at a different rate, depending mainly on electrical charge and size, resulting in spatial separation within the matrix of each molecular species in the sample mixture. Agarose and acrylamide in a cylindrical tube or slab gel are commonly used media for electrophoresis of proteins and nucleic acids. |
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FULL_SYN |
GEL ELECTROPHORESIS Gel Electrophoresis Gel Electropheresis |
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Is_PCDC_AML_Authorized_Value_For_Variable | ||
label |
Gel Electrophoresis |
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Legacy Concept Name |
Gel_Electrophoresis |
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Preferred_Name |
Gel Electrophoresis |
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prefixIRI |
Thesaurus:C18091 |
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Semantic_Type |
Molecular Biology Research Technique |
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UMLS_CUI |
C0596607 |
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subClassOf |