loading...| Preferred Name | Tumor Progression | |
| Synonyms |
Progression Tumor Progression |
|
| Definitions |
A pathologic process in which alterations at the molecular level result in a more aggressive cytologic and phenotypic profile and clinical course of a neoplasm. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17609 |
|
| code |
C17609 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159328 |
|
| Contributing_Source |
CPTAC GDC |
|
| DEFINITION |
A pathologic process in which alterations at the molecular level result in a more aggressive cytologic and phenotypic profile and clinical course of a neoplasm. |
|
| DesignNote |
The process of tumor progression is thought to be driven by clonal evolution. The initiating event is a mutation that gives a cell the ability to divide when it shouldn't. As a result a small group of related cells, called a clone because they are identical to each other, grows. Clonal evolution occurs like a tree with mutations causing many clones to branch off continuously. |
|
| FULL_SYN |
Progression Tumor Progression |
|
| Is_Value_For_GDC_Property | ||
| label |
Tumor Progression |
|
| Legacy Concept Name |
Tumor_Progression |
|
| Maps_To |
Progression |
|
| Preferred_Name |
Tumor Progression |
|
| prefixIRI |
Thesaurus:C17609 |
|
| Semantic_Type |
Pathologic Function |
|
| UMLS_CUI |
C0178874 |
|
| subClassOf |