loading...| Preferred Name |
Aromatase Inhibitor |
|
| Synonyms |
Aromatase Inhibitor Androstenedione Aromatase Inhibitor Aromatase Inhibition Therapy Estrogen Synthase Inhibitor Estrogen Synthetase Inhibitor aromatase inhibitor |
|
| Definitions |
Any substance that inhibits aromatase, an enzyme responsible for the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Inhibition of aromatase results in the suppression of estrogen-regulated processes. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1740 |
|
| ALT_DEFINITION |
A drug that prevents the formation of estradiol, a female hormone, by interfering with an aromatase enzyme. Aromatase inhibitors are used as a type of hormone therapy for postmenopausal women who have hormone-dependent breast cancer. |
|
| CHEBI_ID |
CHEBI:50790 |
|
| code |
C1740 |
|
| Concept_In_Subset | ||
| Contributing_Source |
CTRP |
|
| DEFINITION |
Any substance that inhibits aromatase, an enzyme responsible for the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Inhibition of aromatase results in the suppression of estrogen-regulated processes. |
|
| Display_Name |
Aromatase Inhibitor |
|
| FULL_SYN |
Aromatase Inhibitor Androstenedione Aromatase Inhibitor Aromatase Inhibition Therapy Estrogen Synthase Inhibitor Estrogen Synthetase Inhibitor aromatase inhibitor |
|
| label |
Aromatase Inhibitor |
|
| Legacy Concept Name |
Aromatase_Inhibitor |
|
| Preferred_Name |
Aromatase Inhibitor |
|
| prefixIRI |
Thesaurus:C1740 |
|
| Semantic_Type |
Chemical Viewed Functionally |
|
| UMLS_CUI |
C0593802 |
|
| subClassOf |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C481 |