National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

JAK Inhibitor
Synonyms

Janus Kinase Inhibitor

JAK inhibitors

JAK Inhibitor

Definitions

Any agent that targets, binds to and inhibits the activity of one or more of the Janus kinase family of enzymes.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172200

ALT_DEFINITION

A substance that inhibits the biological action of tyrosine-protein kinase JAK1, an enzyme that plays a key role in certain types of cancer and cytokine signaling

code

C172200

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191670

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191387

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191404

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

ACC/AHA

CTRP

GDC

DEFINITION

Any agent that targets, binds to and inhibits the activity of one or more of the Janus kinase family of enzymes.

Display_Name

JAK Inhibitor

FULL_SYN

Janus Kinase Inhibitor

JAK inhibitors

JAK Inhibitor

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1909

label

JAK Inhibitor

Maps_To

JAK Inhibitor

NCI_Drug_Dictionary_ID

802011

NCI_META_CUI

CL1406090

PDQ_Closed_Trial_Search_ID

802011

PDQ_Open_Trial_Search_ID

802011

Preferred_Name

JAK Inhibitor

prefixIRI

Thesaurus:C172200

Semantic_Type

Pharmacologic Substance

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1967

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129825

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http://purl.obolibrary.org/obo/NCIT_C172200 BERO LOOM