National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Prostaglandin F2alpha
Synonyms

Prostaglandin F2a

(5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dien-1-oic acid

Prostaglandin-F2alpha

Prostaglandin F2alpha

PGF2

PGF2a

PGF2alpha

Definitions

A naturally occurring prostaglandin that stimulates myometrial activity, relaxes the cervix, inhibits corpus luteal steroidogenesis, and induces luteolysis by direct action on the corpus luteum. Expression of prostaglandin F2alpha (PGF2) is elevated in certain types of cancers.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C152070

CHEBI_ID

CHEBI:15553

code

C152070

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

A naturally occurring prostaglandin that stimulates myometrial activity, relaxes the cervix, inhibits corpus luteal steroidogenesis, and induces luteolysis by direct action on the corpus luteum. Expression of prostaglandin F2alpha (PGF2) is elevated in certain types of cancers.

Display_Name

Prostaglandin F2alpha

FULL_SYN

Prostaglandin F2a

(5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dien-1-oic acid

Prostaglandin-F2alpha

Prostaglandin F2alpha

PGF2

PGF2a

PGF2alpha

label

Prostaglandin F2alpha

NCI_META_CUI

CL553279

Preferred_Name

Prostaglandin F2alpha

prefixIRI

Thesaurus:C152070

Semantic_Type

Organic Chemical

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C782

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