Preferred Name |
Enoxaparin |
|
Synonyms |
ENOXAPARIN Enoxaparin enoxaparin |
|
Definitions |
A low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. (NCI04) |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1452 |
|
ALT_DEFINITION |
A drug used to prevent blood clots. It belongs to the family of drugs called anticoagulants. |
|
CAS_Registry |
9005-49-6 |
|
CHEBI_ID |
CHEBI:28304 |
|
Chemical_Formula |
(C14H18NO11)n.C14H18NO11.C12H17NO12S.(C12H16NO13S)n.C12H15NO13S.Na.H.5HO3S |
|
code |
C1452 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 |
|
Contributing_Source |
CTRP FDA HemOnc |
|
DEFINITION |
A low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. (NCI04) |
|
Display_Name |
Enoxaparin |
|
FDA_UNII_Code |
E47C0NF7LV |
|
FULL_SYN |
ENOXAPARIN Enoxaparin enoxaparin |
|
Has_Salt_Form | ||
label |
Enoxaparin |
|
Legacy Concept Name |
Enoxaparin |
|
NCI_Drug_Dictionary_ID |
37880 |
|
NSC Number |
728167 |
|
PDQ_Closed_Trial_Search_ID |
37880 |
|
PDQ_Open_Trial_Search_ID |
37880 |
|
Preferred_Name |
Enoxaparin |
|
prefixIRI |
Thesaurus:C1452 |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0206460 |
|
subClassOf |