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National Cancer Institute Thesaurus
| Preferred Name | Enoxaparin | |
| Synonyms |
ENOXAPARIN Enoxaparin enoxaparin |
|
| Definitions |
A low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1452 |
|
| ALT_DEFINITION |
A drug used to prevent blood clots. It belongs to the family of drugs called anticoagulants.
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|
| CAS_Registry |
9005-49-6
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|
| CHEBI_ID |
CHEBI:28304
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|
| Chemical_Formula |
(C14H18NO11)n.C14H18NO11.C12H17NO12S.(C12H16NO13S)n.C12H15NO13S.Na.H.5HO3S
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|
| code |
C1452
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|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 |
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| Contributing_Source |
CTRP FDA HemOnc
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|
| DEFINITION |
A low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. (NCI04)
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|
| Display_Name |
Enoxaparin
|
|
| FDA_UNII_Code |
E47C0NF7LV
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|
| FULL_SYN |
ENOXAPARIN Enoxaparin enoxaparin
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|
| Has_Salt_Form | ||
| label |
Enoxaparin
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|
| Legacy Concept Name |
Enoxaparin
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|
| NCI_Drug_Dictionary_ID |
37880
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|
| NSC Number |
728167
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| PDQ_Closed_Trial_Search_ID |
37880
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|
| PDQ_Open_Trial_Search_ID |
37880
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| Preferred_Name |
Enoxaparin
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|
| prefixIRI |
Thesaurus:C1452
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0206460
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| subClassOf |
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