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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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Preferred Name | Low Molecular Weight Heparin | |
Synonyms |
Low Molecular Weight Heparin Low-molecular-weight heparin LMWH |
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Definitions |
Substances comprised of fragmented heparin molecules derived from unfractionated heparin that bind to antithrombin III with a molecular weight ranging from 1000 to 10,000 daltons, which causes changes in property from unfractionated heparin, including decreased protein binding, enhanced bioavailability, decreased platelet interaction, and decreased binding to thrombin. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2578 |
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ALT_DEFINITION |
Low-molecular-weight heparin compounds are fractions of heparin that primarily act by inhibiting the activated clotting factor X. Examples include enoxaparin and dalteparin.
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code |
C2578
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Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191406 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
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Contributing_Source |
ACC/AHA CTRP
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DEFINITION |
Substances comprised of fragmented heparin molecules derived from unfractionated heparin that bind to antithrombin III with a molecular weight ranging from 1000 to 10,000 daltons, which causes changes in property from unfractionated heparin, including decreased protein binding, enhanced bioavailability, decreased platelet interaction, and decreased binding to thrombin.
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Display_Name |
Low Molecular Weight Heparin
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FULL_SYN |
Low Molecular Weight Heparin Low-molecular-weight heparin LMWH
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label |
Low Molecular Weight Heparin
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Legacy Concept Name |
Low_Molecular_Weight_Heparin
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Preferred_Name |
Low Molecular Weight Heparin
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prefixIRI |
Thesaurus:C2578
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Semantic_Type |
Classification
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UMLS_CUI |
C0019139
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subClassOf |
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