National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Perflubron

Synonyms

Perfluorooctylbromide

Imagent GI

PERFLUBRON

PFOB

Perflubron

Definitions

A synthetic radiopaque liquid form of perfluorooctyl bromide. Used as a contrast agent for magnetic resonance imaging (MRI), perflubron is also used as a liquid ventilation agent to improve pulmonary gas exchange and lung compliance and may be used in surgery to reduce or eliminate the need for donor blood. Ventilation with perfluorocarbon fluid improves lung function in conditions involving surfactant deficiency and dysfunction, including respiratory distress syndrome and adult respiratory distress syndrome. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1422

CAS_Registry

423-55-2

CHEBI_ID

CHEBI:38803

Chemical_Formula

C8BrF17

code

C1422

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic radiopaque liquid form of perfluorooctyl bromide. Used as a contrast agent for magnetic resonance imaging (MRI), perflubron is also used as a liquid ventilation agent to improve pulmonary gas exchange and lung compliance and may be used in surgery to reduce or eliminate the need for donor blood. Ventilation with perfluorocarbon fluid improves lung function in conditions involving surfactant deficiency and dysfunction, including respiratory distress syndrome and adult respiratory distress syndrome. (NCI04)

FDA_UNII_Code

Q1D0Q7R4D9

FULL_SYN

Perfluorooctylbromide

Imagent GI

PERFLUBRON

PFOB

Perflubron

label

Perflubron

Legacy Concept Name

Perflubron

NCI_Drug_Dictionary_ID

41963

PDQ_Closed_Trial_Search_ID

41963

PDQ_Open_Trial_Search_ID

41963

Preferred_Name

Perflubron

prefixIRI

Thesaurus:C1422

Semantic_Type

Organic Chemical

Pharmacologic Substance

Indicator, Reagent, or Diagnostic Aid

UMLS_CUI

C0162922

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C798

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C390

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