National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Chimera
Synonyms

Chimera

Chimeric

chimeric

Definitions

An organism with tissues derived from two or more genotypes; composed of parts that are of different origin.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14194

ALT_DEFINITION

Having parts of different origins. In medicine, refers to a person, organ, or tissue that contains cells with different genes than the rest of the person, organ, or tissue. This may happen because of a mutation (genetic change) that occurs during development, or as a result of a transplant of cells, organs, or tissues from another person or from a different species. In the laboratory, a chimeric protein can be made by combining two different genes. For example, a chimeric antibody is made by joining antibody genes from two different species, such as human and mouse.

code

C14194

DEFINITION

An organism with tissues derived from two or more genotypes; composed of parts that are of different origin.

DesignNote

A chimera may develop naturally by somatic cell mutation or be created artificially.

FULL_SYN

Chimera

Chimeric

chimeric

label

Chimera

Legacy Concept Name

Chimera

Preferred_Name

Chimera

prefixIRI

Thesaurus:C14194

Semantic_Type

Organism

UMLS_CUI

C0008109

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14376

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