loading...| Preferred Name |
Goserelin Acetate |
|
| Synonyms |
Goserelin Acetate GOSERELIN ACETATE D-Ser(bu(t))(6)azgly(10)-LHRH Acetate ZDX Zoladex |
|
| Definitions |
The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1417 |
|
| Accepted_Therapeutic_Use_For |
Breast Carcinoma; Prostate Carcinoma; Endometriosis |
|
| CAS_Registry |
65807-02-5 |
|
| Chemical_Formula |
C59H84N18O14.C2H4O2 |
|
| code |
C1417 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
CTRP FDA GDC |
|
| DEFINITION |
The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04) |
|
| Display_Name |
Goserelin Acetate |
|
| FDA_UNII_Code |
6YUU2PV0U8 |
|
| FULL_SYN |
Goserelin Acetate GOSERELIN ACETATE D-Ser(bu(t))(6)azgly(10)-LHRH Acetate ZDX Zoladex |
|
| Has_Free_Acid_Or_Base_Form | ||
| Has_Target | ||
| Is_Value_For_GDC_Property | ||
| label |
Goserelin Acetate |
|
| Legacy Concept Name |
Goserelin_Acetate |
|
| Maps_To |
Goserelin Acetate |
|
| NCI_Drug_Dictionary_ID |
40224 |
|
| NSC Number |
606864 |
|
| PDQ_Closed_Trial_Search_ID |
40224 |
|
| PDQ_Open_Trial_Search_ID |
40224 |
|
| Preferred_Name |
Goserelin Acetate |
|
| prefixIRI |
Thesaurus:C1417 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance |
|
| UMLS_CUI |
C0700476 |
|
| subClassOf |