Link to this page
National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
Jump to:
| Preferred Name | Etidronic Acid | |
| Synonyms |
(1-Hydroxyethylidene)diphosphonic Acid (1-Hydroxyethylidene)bisphosphonic Acid Etidronic Acid Ethane-1-hydroxy-1,1-diphosphonic acid ETIDRONIC ACID Ethane-1-hydroxy-1,1-diphosphonic Acid EHDP Etidronate etidronate |
|
| Definitions |
As a member of the family of drugs known as bisphosphonates, etidronate differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts. (NCI) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1332 |
|
| ALT_DEFINITION |
A drug that belongs to the family of drugs called bisphosphonates. Bisphosphonates are used as treatment for hypercalcemia (abnormally high levels of calcium in the blood) and for cancer that has spread to the bone (bone metastases).
|
|
| CAS_Registry |
2809-21-4
|
|
| CHEBI_ID |
CHEBI:4907
|
|
| Chemical_Formula |
C2H8O7P2
|
|
| code |
C1332
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
As a member of the family of drugs known as bisphosphonates, etidronate differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts. (NCI)
|
|
| FDA_UNII_Code |
M2F465ROXU
|
|
| FULL_SYN |
(1-Hydroxyethylidene)diphosphonic Acid (1-Hydroxyethylidene)bisphosphonic Acid Etidronic Acid Ethane-1-hydroxy-1,1-diphosphonic acid ETIDRONIC ACID Ethane-1-hydroxy-1,1-diphosphonic Acid EHDP Etidronate etidronate
|
|
| Has_Salt_Form | ||
| label |
Etidronic Acid
|
|
| Legacy Concept Name |
Etidronate
|
|
| NCI_Drug_Dictionary_ID |
39239
|
|
| NSC Number |
227995
|
|
| PDQ_Closed_Trial_Search_ID |
39239
|
|
| PDQ_Open_Trial_Search_ID |
39239
|
|
| Preferred_Name |
Etidronic Acid
|
|
| prefixIRI |
Thesaurus:C1332
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0086268
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping