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National Cancer Institute Thesaurus
| Preferred Name | Thymopentin | |
| Synonyms |
THYMOPENTIN N-(N-(N-(N(2)-L-Arginyl-L-Lysyl)-L-alpha-Aspartyl)-L-Valyl)-L-Tyrosine Thymopentin N-[N-[N-(N{2}-L-Arginyl-L-lysyl)-L-alpha-aspartyl]-L-valyl]-L-tyrosine Sintomodulina Immunox Mepentil ORF-15244 Timunox |
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| Definitions |
A synthetic pentapeptide which is the active site of the naturally occurring hormone thymopoietin with immunomodulating properties. Thymopentin enhances the production of thymic T cells and may help restore immunocompetence in immunosuppressed subjects. This agent also augments the effects of ionizing radiation by arresting cancer cells in the G2/M phase of the cell cycle. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1294 |
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| CAS_Registry |
69558-55-0
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|
| Chemical_Formula |
C30H49N9O9
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|
| code |
C1294
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|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
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| Contributing_Source |
FDA GDC
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|
| DEFINITION |
A synthetic pentapeptide which is the active site of the naturally occurring hormone thymopoietin with immunomodulating properties. Thymopentin enhances the production of thymic T cells and may help restore immunocompetence in immunosuppressed subjects. This agent also augments the effects of ionizing radiation by arresting cancer cells in the G2/M phase of the cell cycle. (NCI04)
|
|
| FDA_UNII_Code |
O3Y80ZF13F
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|
| FULL_SYN |
THYMOPENTIN N-(N-(N-(N(2)-L-Arginyl-L-Lysyl)-L-alpha-Aspartyl)-L-Valyl)-L-Tyrosine Thymopentin N-[N-[N-(N{2}-L-Arginyl-L-lysyl)-L-alpha-aspartyl]-L-valyl]-L-tyrosine Sintomodulina Immunox Mepentil ORF-15244 Timunox
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|
| Is_Value_For_GDC_Property | ||
| label |
Thymopentin
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|
| Legacy Concept Name |
Thymopentin
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|
| Maps_To |
Thymopentin
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|
| NCI_Drug_Dictionary_ID |
41655
|
|
| NSC Number |
645363
|
|
| PDQ_Closed_Trial_Search_ID |
41655
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|
| PDQ_Open_Trial_Search_ID |
41655
|
|
| Preferred_Name |
Thymopentin
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|
| prefixIRI |
Thesaurus:C1294
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|
| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance
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|
| UMLS_CUI |
C0080225
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| subClassOf |
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