National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Jump to:
loading...
Preferred Name

Transmissible Spongiform Encephalopathy
Synonyms

Transmissible Spongiform Encephalopathy

Spongiform Encephalopathy

Transmissible Spongiform Encephalopathy(TSE)

Prion Disease
Definitions

A transmissible, infectious disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128346
ALT_DEFINITION

A group of rare degenerative brain disorders associated with prions for example Creutzfeldt-Jakob disease (CJD) or Bovine Spongiform Encephalopathy (BSE).

A transmissible, infectious disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal.
code

C128346
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62596

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128453

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54450
Contributing_Source

FDA

NICHD
DEFINITION

A transmissible, infectious disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal.
FULL_SYN

Transmissible Spongiform Encephalopathy

Spongiform Encephalopathy

Transmissible Spongiform Encephalopathy(TSE)

Prion Disease
label

Transmissible Spongiform Encephalopathy
Preferred_Name

Transmissible Spongiform Encephalopathy
prefixIRI

Thesaurus:C128346
Semantic_Type

Disease or Syndrome
UMLS_CUI

C0162534
xRef

IMDRF:E1905
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26920

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27582
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display