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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Tazobactam Sodium | |
| Synonyms |
Tazobactam Sodium TAZOBACTAM SODIUM |
|
| Definitions |
The sodium salt form of tazobactam, a penicillanic acid sulfone derivative and beta-lactamase inhibitor with antibacterial activity. Tazobactam contains a beta-lactam ring and irreversibly binds to beta-lactamase at or near its active site. This protects other beta-lactam antibiotics from beta-lactamase catalysis. This drug is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1242 |
|
| CAS_Registry |
89785-84-2
|
|
| Chemical_Formula |
C10H11N4O5S.Na
|
|
| code |
C1242
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
The sodium salt form of tazobactam, a penicillanic acid sulfone derivative and beta-lactamase inhibitor with antibacterial activity. Tazobactam contains a beta-lactam ring and irreversibly binds to beta-lactamase at or near its active site. This protects other beta-lactam antibiotics from beta-lactamase catalysis. This drug is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms.
|
|
| FDA_UNII_Code |
UXA545ABTT
|
|
| FULL_SYN |
Tazobactam Sodium TAZOBACTAM SODIUM
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Tazobactam Sodium
|
|
| Legacy Concept Name |
Tazobactam
|
|
| NCI_Drug_Dictionary_ID |
41540
|
|
| PDQ_Closed_Trial_Search_ID |
41540
|
|
| PDQ_Open_Trial_Search_ID |
41540
|
|
| Preferred_Name |
Tazobactam Sodium
|
|
| prefixIRI |
Thesaurus:C1242
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic
|
|
| UMLS_CUI |
C3713846
|
|
| subClassOf |
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