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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Arylsulfatase A | |
| Synonyms |
Cerebroside-Sulfatase Arylsulfatase A Cerebroside 3-Sulfatase ARSA ASA EC 3.1.6.8 |
|
| Definitions |
Arylsulfatase A (507 aa, ~54 kDa) is encoded by the human ARSA gene. This protein is involved in the hydrolysis of cerebroside sulfate. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103932 |
|
| code |
C103932
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP
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|
| DEFINITION |
Arylsulfatase A (507 aa, ~54 kDa) is encoded by the human ARSA gene. This protein is involved in the hydrolysis of cerebroside sulfate.
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|
| DesignNote |
Mutation of the SUMF1 gene results in misprocessing of arylsulfatase A and all other sulfatases leading to multiple sulfatase deficiency. (UniProt) The conversion of a cysteine residue in eukaryotes to 3-oxoalanine (also known as C-formylglycine, FGly), is critical for catalytic activity. (UniProt)
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|
| Display_Name |
Arylsulfatase A
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|
| FULL_SYN |
Cerebroside-Sulfatase Arylsulfatase A Cerebroside 3-Sulfatase ARSA ASA EC 3.1.6.8
|
|
| label |
Arylsulfatase A
|
|
| OMIM_Number |
607574
|
|
| Preferred_Name |
Arylsulfatase A
|
|
| prefixIRI |
Thesaurus:C103932
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|
| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme
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|
| Swiss_Prot |
P15289
|
|
| UMLS_CUI |
C0007804
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| subClassOf |
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