loading...| Preferred Name |
AL amyloidosis |
|
| Synonyms |
amyloidosis primary systemic primary AL amyloidosis primary systemic AL amyloidosis systemic AL amyloidsis amyloidosis AL primary systemic amyloidosis Light chain amyloidosis Light-chain amyloidosis primary amyloidosis |
|
| Definitions |
AL Amyloidosis is a plasma cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains usually produced by a plasma cell tumor. It usually presents as primary systemic amyloidosis (PSA) with multiple organ involvement and less frequently as primary localized amyloidosis (PLA) restricted to a single organ. |
|
| ID |
http://purl.obolibrary.org/obo/MONDO_0019438 |
|
| closeMatch | ||
| database_cross_reference |
GARD:5797 DOID:0080933 MedDRA:10036673 NCIT:C158963 UMLS:C0268381 icd11.foundation:113043090 MESH:C531616 Orphanet:85443 |
|
| definition |
AL Amyloidosis is a plasma cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains usually produced by a plasma cell tumor. It usually presents as primary systemic amyloidosis (PSA) with multiple organ involvement and less frequently as primary localized amyloidosis (PLA) restricted to a single organ. |
|
| exactMatch |
http://purl.obolibrary.org/obo/Orphanet_85443 http://purl.obolibrary.org/obo/DOID_0080933 http://purl.obolibrary.org/obo/NCIT_C158963 |
|
| has_exact_synonym |
Light-chain amyloidosis primary amyloidosis |
|
| has_related_synonym |
amyloidosis primary systemic primary AL amyloidosis primary systemic AL amyloidosis systemic AL amyloidsis amyloidosis AL primary systemic amyloidosis Light chain amyloidosis |
|
| IAO_0000233 | ||
| id |
MONDO:0019438 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo#ordo_disease http://purl.obolibrary.org/obo/mondo#rare http://purl.obolibrary.org/obo/mondo#nord_rare http://purl.obolibrary.org/obo/mondo#orphanet_rare |
|
| label |
AL amyloidosis |
|
| notation |
MONDO:0019438 |
|
| prefLabel |
AL amyloidosis |
|
| treeView |
http://purl.obolibrary.org/obo/MONDO_0005071 http://purl.obolibrary.org/obo/MONDO_0016330 http://purl.obolibrary.org/obo/MONDO_0016345 |
|
| excluded subClassOf | ||
| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0005071 http://purl.obolibrary.org/obo/MONDO_0016330 http://purl.obolibrary.org/obo/MONDO_0016345 |