loading...| Preferred Name | carcinoid tumor | |
| Synonyms |
neuroendocrine neoplasm G1 neuroendocrine tumor G1 carcinoid neuroendocrine tumour G1 carcinoid tumour (disease) NET G1 carcinoid tumor (disease) carcinoid tumor |
|
| Definitions |
A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement. Editor note: In NCIT all carcinoid tumors are grade 1, but the name is sometimes used more broadly in other sources |
|
| ID |
http://purl.obolibrary.org/obo/MONDO_0005369 |
|
| comment |
Editor note: In NCIT all carcinoid tumors are grade 1, but the name is sometimes used more broadly in other sources |
|
| database_cross_reference |
MESH:D002276 EFO:0004243 ICD9:209.60 NCIT:C2915 HP:0100570 ICDO:8240/3 SCTID:443492008 ICDO:8241/3 |
|
| definition |
A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement. |
|
| exactMatch |
http://identifiers.org/snomedct/443492008 |
|
| has_exact_synonym |
neuroendocrine neoplasm G1 neuroendocrine tumor G1 carcinoid neuroendocrine tumour G1 carcinoid tumour (disease) NET G1 carcinoid tumor (disease) carcinoid tumor |
|
| IAO_0000589 |
carcinoid tumor (disease) |
|
| id |
MONDO:0005369 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo#rare |
|
| label |
carcinoid tumor |
|
| notation |
MONDO:0005369 |
|
| prefLabel |
carcinoid tumor |
|
| treeView | ||
| subClassOf |