Preferred Name |
ticlopidine |
|
Synonyms |
|
|
Definitions |
A thienopyridine derivative with anticoagulant activity. Ticlopidine inhibits adenosine-diphosphate (ADP) binding to its platelet receptor. This prevents ADP activation and inhibits platelet expression of the glycoprotein (GP) IIb/IIIA receptors, binding of fibrinogen to platelet glycoprotein GP IIb-IIIa and platelet-platelet interaction. This results in increased bleeding time. [url:http://purl.obolibrary.org/obo/NCIT_C61972] |
|
ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02863 |
|
definition |
A thienopyridine derivative with anticoagulant activity. Ticlopidine inhibits adenosine-diphosphate (ADP) binding to its platelet receptor. This prevents ADP activation and inhibits platelet expression of the glycoprotein (GP) IIb/IIIA receptors, binding of fibrinogen to platelet glycoprotein GP IIb-IIIa and platelet-platelet interaction. This results in increased bleeding time. [url:http://purl.obolibrary.org/obo/NCIT_C61972] |
|
label |
ticlopidine |
|
MIO_ID |
MIO:02863 |
|
prefLabel |
ticlopidine |
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reference |
NCIT:C61972 |
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subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02641 |