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Myocardial Infarction Ontology
Last uploaded:
December 18, 2024
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Preferred Name | eplerenone | |
Synonyms |
9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, Methyl Ester inspra |
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Definitions |
A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerenone is used in the treatment of hypertension and congestive heart failure. [url:http://purl.obolibrary.org/obo/NCIT_C47513] |
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ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02118 |
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definition |
A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerenone is used in the treatment of hypertension and congestive heart failure. [url:http://purl.obolibrary.org/obo/NCIT_C47513]
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label |
eplerenone
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MIO_ID |
MIO:02118
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prefLabel |
eplerenone
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reference |
CHEBI:31547 NCIT:C47513 UMLS:C0961485
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synonyms |
9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, Methyl Ester inspra
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subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01066 |
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