Preferred Name |
autoimmune lymphoproliferative syndrome |
|
Synonyms |
Canale-Smith syndrome ALPS |
|
Definitions |
A hypersensitivity reaction type IV disease that is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). It is characterized by the production of an abnormally large number of lymphocytes. Accumulation of excess lymphocytes results in enlargement of the lymph nodes, the liver, and the spleen. Xref MGI. OMIM mapping confirmed by DO. [SN]. |
|
ID |
http://purl.obolibrary.org/obo/DOID_6688 |
|
comment |
Xref MGI. OMIM mapping confirmed by DO. [SN]. |
|
database_cross_reference |
ICD9CM:279.41 NCI:C37864 ORDO:3261 OMIM:601859 SNOMEDCT_US_2021_09_01:702444009 ICD10CM:D89.82 UMLS_CUI:C1328840 MESH:D056735 GARD:8686 |
|
definition |
A hypersensitivity reaction type IV disease that is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). It is characterized by the production of an abnormally large number of lymphocytes. Accumulation of excess lymphocytes results in enlargement of the lymph nodes, the liver, and the spleen. Xref MGI. OMIM mapping confirmed by DO. [SN]. |
|
has exact match |
MESH:D056735 |
|
has_exact_synonym |
Canale-Smith syndrome ALPS |
|
has_obo_namespace |
disease_ontology |
|
IAO_0000115 |
A hypersensitivity reaction type IV disease that is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). It is characterized by the production of an abnormally large number of lymphocytes. Accumulation of excess lymphocytes results in enlargement of the lymph nodes, the liver, and the spleen. |
|
id |
DOID:6688 |
|
in_subset | ||
label |
autoimmune lymphoproliferative syndrome |
|
notation |
DOID:6688 |
|
note |
A hypersensitivity reaction type IV disease that is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). It is characterized by the production of an abnormally large number of lymphocytes. Accumulation of excess lymphocytes results in enlargement of the lymph nodes, the liver, and the spleen. Xref MGI. OMIM mapping confirmed by DO. [SN]. |
|
prefLabel |
autoimmune lymphoproliferative syndrome |
|
subClassOf |