Medical Subject Headings

Last uploaded: August 28, 2024

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Preferred Name	Leptin
Synonyms	Ob Protein Gene Product, Obese Obese Gene Product Ob Gene Product Gene Product, Ob Obese Protein
Definitions	A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
ID	http://purl.bioontology.org/ontology/MESH/D020738
altLabel	Ob Protein Gene Product, Obese Obese Gene Product Ob Gene Product Gene Product, Ob Obese Protein
AQL	AA AD AE AG AI AN BI BL CF CH CL CS DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR
cui	C0299583
DC	1
definition	A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
DX	20000101
HN	2000; use LEPTIN (NM) 1995-1999
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	0
Machine permutation	2000; OB PROTEIN (now LEPTIN) was indexed under PROTEINS 1995-1999
Mapped from	http://purl.bioontology.org/ontology/MESH/C484843 http://purl.bioontology.org/ontology/MESH/C410793 http://purl.bioontology.org/ontology/MESH/C122136 http://purl.bioontology.org/ontology/MESH/C581199 http://purl.bioontology.org/ontology/MESH/C487164 http://purl.bioontology.org/ontology/MESH/C487163 http://purl.bioontology.org/ontology/MESH/C521086 http://purl.bioontology.org/ontology/MESH/C418217 http://purl.bioontology.org/ontology/MESH/C000630546 http://purl.bioontology.org/ontology/MESH/C549021 http://purl.bioontology.org/ontology/MESH/C000729372 http://purl.bioontology.org/ontology/MESH/C415771 http://purl.bioontology.org/ontology/MESH/C000629008
MDA	19991103
MMR	20070709
MN	D12.644.276.024.500 D12.644.548.011.500 D06.472.699.042.500 D23.529.024.500 D12.776.467.024.500
notation	D020738
prefLabel	Leptin
TERMUI	T279126 T279124 T279125 T279123 T279127
TH	NLM (2000)
tui	T125 T116
subClassOf	http://purl.bioontology.org/ontology/MESH/D054392

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/SCTSPA/414601001	SCTSPA	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/414601001	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020738	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000170333	NDFRT	CUI
http://purl.bioontology.org/ontology/LNC/MTHU009760	LOINC	CUI
http://purl.bioontology.org/ontology/CSP/4008-0059	CRISP	CUI
http://purl.bioontology.org/ontology/LNC/LP19488-3	LOINC	CUI
http://purl.bioontology.org/ontology/RXNORM/1441651	RXNORM	CUI
http://purl.bioontology.org/ontology/OMIM/164160	OMIM	LOOM
http://www.uniprot.org/uniprot/P41159	CHEAR	LOOM
http://www.uniprot.org/uniprot/P41159	HHEAR	LOOM
http://purl.obolibrary.org/obo/NCIT_C46081	BERO	LOOM
http://purl.obolibrary.org/obo/IMR_0000051	HOIP	LOOM
http://purl.obolibrary.org/obo/IMR_0000051	TXPO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D020738	RH-MESH	LOOM
http://www.ncbi.nlm.nih.gov/gene/16846	NIFSTD	LOOM
http://scai.fraunhofer.de/CSEO#CSEO_00001104	CSEO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.276.024.500	RH-MESH	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Leptin	APANEUROCLUSTER	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Leptin	APAONTO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D06.472.699.042.500	RH-MESH	LOOM
http://localhost/plosthes.2017-1#1486	PLOSTHES	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0299583	OCHV	LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01662	MIO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/414601001	SNOMEDCT	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00019180	PMAPP-PMO	LOOM
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Leptin	PCAO	LOOM
http://id.nlm.nih.gov/mesh/D020738	MDM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.548.011.500	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU009760	LOINC	LOOM
http://purl.bioontology.org/ontology/CSP/4008-0059	CRISP	LOOM
http://www.ebi.ac.uk/efo/EFO_0003199	CCONT	LOOM
http://www.ebi.ac.uk/efo/EFO_0003199	EFO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.529.024.500	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D020738	BERO	LOOM
http://purl.obolibrary.org/obo/OMIT_0020586	OMIT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C46081	NCIT	LOOM
https://go.drugbank.com/drugs/DB05098	MDM	LOOM
http://www.orpha.net/ORDO/Orphanet_123034	ORDO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.467.024.500	RH-MESH	LOOM
http://uri.neuinfo.org/nif/nifstd/nlx_mol_090806	NIFSTD	LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Leptin	SEPON	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#27803	OCHV	LOOM
http://purl.obolibrary.org/obo/CHEBI_81571	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_81571	UPHENO	LOOM
http://purl.obolibrary.org/obo/CHEBI_81571	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_81571	ZP	LOOM
http://purl.bioontology.org/ontology/LNC/LP19488-3	LOINC	LOOM
http://www.projecthalo.com/aura#Leptin	AURA	LOOM
http://purl.obolibrary.org/obo/PR_000009758	PR	LOOM
http://purl.obolibrary.org/obo/PR_000009758	PDRO	LOOM
http://purl.obolibrary.org/obo/PR_000009758	OBI	LOOM
http://purl.obolibrary.org/obo/PR_000009758	BMONT	LOOM
http://purl.obolibrary.org/obo/PR_000009758	UPHENO	LOOM
http://purl.obolibrary.org/obo/PR_000009758	NIFSTD	LOOM
http://purl.obolibrary.org/obo/PR_000009758	OBA	LOOM
http://purl.bioontology.org/ontology/RXNORM/1441651	RXNORM	LOOM
http://purl.jp/bio/4/id/200906035272710354	IOBC	LOOM