Medical Subject Headings

Last uploaded: August 28, 2024

Preferred Name	Poloxamer
Synonyms	Poloxamer 2930s 213s, Poloxamer Poloxamer 338s Pluronic F108 Pluronic L-101 Pluronic L81 Pluronic F68s Poloxamer 213 Pluronic L 121 Poloxamer 188s Pluronic L 81 Poloxamer 407 Poloxalkol Poloxalkols 407s, Poloxamer F68s, Pluronic Pluronic L-81 Poloxamers 2930s, Poloxamer Pluronic F 68 Pluronic F127 Pluronic L101 Poloxamer 2930 Poloxamer 188 Pluronic Pluronic L-121 Poloxamer 213s Poloxamer 338 Poloxamer 407s Pluronic F-68 alpha-Hydro-omega-hydroxypoly(oxyethylene)a-poly(oxopropylene)b-poly(oxyethylene)a block copolymer Pluronic L121 188s, Poloxamer Pluronic L 101 Pluronic F-108 Pluronic F 108 Pluronic F68 Pluronic F 127 Pluronics 338s, Poloxamer Pluronic F-127
Definitions	A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
ID	http://purl.bioontology.org/ontology/MESH/D020442
altLabel	Poloxamer 2930s 213s, Poloxamer Poloxamer 338s Pluronic F108 Pluronic L-101 Pluronic L81 Pluronic F68s Poloxamer 213 Pluronic L 121 Poloxamer 188s Pluronic L 81 Poloxamer 407 Poloxalkol Poloxalkols 407s, Poloxamer F68s, Pluronic Pluronic L-81 Poloxamers 2930s, Poloxamer Pluronic F 68 Pluronic F127 Pluronic L101 Poloxamer 2930 Poloxamer 188 Pluronic Pluronic L-121 Poloxamer 213s Poloxamer 338 Poloxamer 407s Pluronic F-68 alpha-Hydro-omega-hydroxypoly(oxyethylene)a-poly(oxopropylene)b-poly(oxyethylene)a block copolymer Pluronic L121 188s, Poloxamer Pluronic L 101 Pluronic F-108 Pluronic F 108 Pluronic F68 Pluronic F 127 Pluronics 338s, Poloxamer Pluronic F-127
AQL	AA AD AE AN CH CL CS EC HI IP ME PD PK PO RE SD ST TO TU
cui	C0086826 C0032256 C0600612 C0086827 C0032253 C0600611 C0032397 C0032254 C0032252 C0032255 C0600614 C0032257 C0032251 C0600615 C0600613
DC	1
definition	A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
DX	19990101
HN	99; for POLOXAMERS use POLOXALENE 1974-98
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	106392-12-5 0
isa	http://purl.bioontology.org/ontology/MESH/D005079 http://purl.bioontology.org/ontology/MESH/D013501
LT	TRD
Machine permutation	99; for POLOXAMERS see POLOXALENE 1974-98
Mapped from	http://purl.bioontology.org/ontology/MESH/C488695 http://purl.bioontology.org/ontology/MESH/C514452 http://purl.bioontology.org/ontology/MESH/C551509 http://purl.bioontology.org/ontology/MESH/C018643 http://purl.bioontology.org/ontology/MESH/C000706807 http://purl.bioontology.org/ontology/MESH/C000608702 http://purl.bioontology.org/ontology/MESH/C475673 http://purl.bioontology.org/ontology/MESH/C475674 http://purl.bioontology.org/ontology/MESH/C000608703 http://purl.bioontology.org/ontology/MESH/C569797 http://purl.bioontology.org/ontology/MESH/C519610 http://purl.bioontology.org/ontology/MESH/C000612848 http://purl.bioontology.org/ontology/MESH/C480965 http://purl.bioontology.org/ontology/MESH/C539704 http://purl.bioontology.org/ontology/MESH/C512681 http://purl.bioontology.org/ontology/MESH/C000615751 http://purl.bioontology.org/ontology/MESH/C000620792 http://purl.bioontology.org/ontology/MESH/C527143 http://purl.bioontology.org/ontology/MESH/C487707
MDA	19980610
MMR	20200527
MN	D25.720.741.667 D02.033.455.250.700.682 J01.637.051.720.741.667 D05.750.741.667
notation	D020442
PA	D005079 D013501
prefLabel	Poloxamer
TERMUI	T060354 T060366 T060361 T060363 T060365 T060356 T060355 T060358 T060359 T060357 T060367 T060360 T060364 T060369 T001004281 T060362 T060368
TH	NLM (1999) USAN (1971) NLM (2021) INN (19XX) BAN (19XX)
tui	T109 T122 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D011092

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MSHFRE/D020442	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020442	MSHFRE	CUI
http://purl.bioontology.org/ontology/SCTSPA/395948003	SCTSPA	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020442	MSHFRE	CUI
http://purl.bioontology.org/ontology/VANDF/4020350	VANDF	CUI
http://purl.bioontology.org/ontology/RXNORM/155156	RXNORM	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020442	MSHFRE	CUI
http://purl.bioontology.org/ontology/VANDF/4018205	VANDF	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/395948003	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020442	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146539	NDFRT	CUI
http://purl.bioontology.org/ontology/SCTSPA/781057006	SCTSPA	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/781057006	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/RXNORM/155152	RXNORM	CUI
http://purl.bioontology.org/ontology/NDDF/010110	NDDF	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000179563	NDFRT	CUI
http://purl.bioontology.org/ontology/RXNORM/1364384	RXNORM	CUI
http://purl.bioontology.org/ontology/NDDF/012239	NDDF	CUI
http://purl.bioontology.org/ontology/RXNORM/155155	RXNORM	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020442	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148184	NDFRT	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000179564	NDFRT	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147367	NDFRT	CUI
http://purl.bioontology.org/ontology/NDDF/001178	NDDF	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020442	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000005921	NDFRT	CUI
http://purl.bioontology.org/ontology/VANDF/4019115	VANDF	CUI
http://purl.obolibrary.org/obo/CHEBI_32026	CHEBI	LOOM
http://purl.obolibrary.org/obo/DRON_01002941	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_32026	DRON	LOOM
http://purl.obolibrary.org/obo/MESH_D020442	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D020442	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#J01.637.051.720.741.667	RH-MESH	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015743	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/RXNORM/155156	RXNORM	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147367	NDFRT	LOOM
http://purl.bioontology.org/ontology/NDDF/001178	NDDF	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.033.455.250.700.682	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D05.750.741.667	RH-MESH	LOOM
http://purl.obolibrary.org/obo/DRON_01002941	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_32026	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_32026	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_32026	DDSS	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D25.720.741.667	RH-MESH	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#42319	OCHV	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0600615	OCHV	LOOM
http://purl.obolibrary.org/obo/OMIT_0020326	OMIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C178536	BERO	LOOM
http://purl.bioontology.org/ontology/VANDF/4019115	VANDF	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178536	NCIT	LOOM
http://psink.de/scio/Poloxamer	SCIO	LOOM