loading...| Preferred Name |
Troponin I |
|
| Synonyms |
Troponin I3 Troponin I1 Troponin-I Troponin I2 |
|
| Definitions |
A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D019210 |
|
| altLabel |
Troponin I3 Troponin I1 Troponin-I Troponin I2 |
|
| AN |
TROPONIN C & TROPONIN T are also available |
|
| AQL |
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
| cui |
C4279927 C0077401 C4279928 C4279926 |
|
| DC |
1 |
|
| definition |
A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY. |
|
| DX |
19970101 |
|
| HN |
97; was TROPONIN I (NM) 1975-96 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
0 |
|
| Machine permutation |
97; TROPONIN I was indexed under TROPONIN 1979-96 & MUSCLE PROTEINS 1975-78 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C000707028 http://purl.bioontology.org/ontology/MESH/C581522 http://purl.bioontology.org/ontology/MESH/C061291 http://purl.bioontology.org/ontology/MESH/C000708943 http://purl.bioontology.org/ontology/MESH/C518658 |
|
| MDA |
19960610 |
|
| MMR |
20160706 |
|
| MN |
D05.750.078.730.825.925 D12.776.220.525.825.925 D05.500.945.925 D12.776.210.500.910.925 |
|
| notation |
D019210 |
|
| OL |
use TROPONIN I (NM) to search TROPONIN I 1980-96 |
|
| prefLabel |
Troponin I |
|
| TERMUI |
T057231 T057232 T000901398 T000901400 T000901399 |
|
| TH |
NLM (1997) NLM (2017) |
|
| tui |
T116 T123 |
|
| subClassOf |