loading...| Preferred Name | Electroporation | |
| Synonyms |
Irreversible Electroporation Electropermeabilisation Electric Field Mediated Cell Permeabilization Reversible Electroporation Electroporation, Irreversible Electroporation, Reversible Electric Field-Mediated Cell Permeabilization |
|
| Definitions |
Application of electric pulses to cells in doses that cause only temporary permeabilization of CELL MEMBRANES. A technique in which electric pulses, in kilovolts per centimeter and of microsecond-to-millisecond duration, cause a loss of the semipermeability of CELL MEMBRANES, thus leading to ion leakage, escape of metabolites, and increased uptake by cells of drugs, molecular probes, and DNA. Depending on the dosage, the formation of openings in the cell membranes caused by the electric pulses may or may not be reversible. Cell permeabilization induced by higher intensity voltages that cause irreparable cell membrane openings which triggers APOPTOSIS. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D018274 |
|
| altLabel |
Irreversible Electroporation Electropermeabilisation Electric Field Mediated Cell Permeabilization Reversible Electroporation Electroporation, Irreversible Electroporation, Reversible Electric Field-Mediated Cell Permeabilization |
|
| AQL |
CL EC ES HI IS MT SN ST TD VE |
|
| cui |
C5691430 C0206691 C4319935 |
|
| DC |
1 |
|
| definition |
Application of electric pulses to cells in doses that cause only temporary permeabilization of CELL MEMBRANES. A technique in which electric pulses, in kilovolts per centimeter and of microsecond-to-millisecond duration, cause a loss of the semipermeability of CELL MEMBRANES, thus leading to ion leakage, escape of metabolites, and increased uptake by cells of drugs, molecular probes, and DNA. Depending on the dosage, the formation of openings in the cell membranes caused by the electric pulses may or may not be reversible. Cell permeabilization induced by higher intensity voltages that cause irreparable cell membrane openings which triggers APOPTOSIS. |
|
| DX |
19940101 |
|
| HN |
94 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000379 http://purl.bioontology.org/ontology/MESH/Q000706 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 |
|
| Inverse of RO | ||
| Machine permutation |
94 |
|
| MDA |
19930603 |
|
| MMR |
20220408 |
|
| MN |
E05.301.500 E05.242.448 E05.200.500.454 |
|
| notation |
D018274 |
|
| prefLabel |
Electroporation |
|
| TERMUI |
T054576 T667446 T001113088 T001113087 T001113084 |
|
| TH |
NLM (2023) NLM (1994) NLM (2007) |
|
| tui |
T059 |
|
| subClassOf |