loading...| Preferred Name | Receptors, Leukocyte-Adhesion | |
| Synonyms |
Leu CAM Receptor Family Leukocyte Adhesion Receptor Family Leukocyte-Adhesion Receptor Receptors, Leukocyte Adhesion Leukocyte Adhesion Receptors Receptor Family, Leu-CAM Leukocyte Adhesion Receptor Leukocyte-Adhesion Receptor Family Receptor, Leukocyte-Adhesion Leukocyte-Adhesion Receptors Leu-CAM Receptor Family Family, Leu-CAM Receptor |
|
| Definitions |
Family of proteins associated with the capacity of LEUKOCYTES to adhere to each other and to certain substrata, e.g., the C3bi component of complement. Members of this family are the LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; (LFA-1), the MACROPHAGE-1 ANTIGEN; (Mac-1), and the INTEGRIN ALPHAXBETA2 or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited LEUKOCYTE-ADHESION DEFICIENCY SYNDROME, which is characterized by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D016028 |
|
| altLabel |
Leu CAM Receptor Family Leukocyte Adhesion Receptor Family Leukocyte-Adhesion Receptor Receptors, Leukocyte Adhesion Leukocyte Adhesion Receptors Receptor Family, Leu-CAM Leukocyte Adhesion Receptor Leukocyte-Adhesion Receptor Family Receptor, Leukocyte-Adhesion Leukocyte-Adhesion Receptors Leu-CAM Receptor Family Family, Leu-CAM Receptor |
|
| AQL |
AD AG AI AN BI BL CH CL DE GE HI IM IP ME PH RE TU UL |
|
| cui |
C0034822 |
|
| DC |
1 |
|
| definition |
Family of proteins associated with the capacity of LEUKOCYTES to adhere to each other and to certain substrata, e.g., the C3bi component of complement. Members of this family are the LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; (LFA-1), the MACROPHAGE-1 ANTIGEN; (Mac-1), and the INTEGRIN ALPHAXBETA2 or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited LEUKOCYTE-ADHESION DEFICIENCY SYNDROME, which is characterized by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells. |
|
| DX |
19900101 |
|
| FX |
D018370 |
|
| HN |
90 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
| Inverse of RB |
0 |
|
| Inverse of RO | ||
| Machine permutation |
90 |
|
| MDA |
19890707 |
|
| MMR |
20030709 |
|
| MN |
D12.776.543.750.705.408.600 |
|
| notation |
D016028 |
|
| prefLabel |
Receptors, Leukocyte-Adhesion |
|
| TERMUI |
T047596 T047595 T490160 T047597 T047594 |
|
| TH |
NLM (1990) NLM (1994) NLM (2003) |
|
| tui |
T116 T129 T192 |
|
| subClassOf |