Medical Subject Headings

Last uploaded: August 28, 2024

Preferred Name	Ryanodine
Synonyms	Ryanodol, 3-(1H-pyrrole-2-carboxylate)
Definitions	A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
ID	http://purl.bioontology.org/ontology/MESH/D012433
altLabel	Ryanodol, 3-(1H-pyrrole-2-carboxylate)
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0035983
DC	1
definition	A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
DX	19910101
HN	91(75); was see under ALKALOIDS 1975-90
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	15662-33-6
Machine permutation	91; was see under ALKALOIDS 1975-90
Mapped from	http://purl.bioontology.org/ontology/MESH/C113821 http://purl.bioontology.org/ontology/MESH/C087174 http://purl.bioontology.org/ontology/MESH/C502871 http://purl.bioontology.org/ontology/MESH/C062838 http://purl.bioontology.org/ontology/MESH/C474026 http://purl.bioontology.org/ontology/MESH/C000608459 http://purl.bioontology.org/ontology/MESH/C091220 http://purl.bioontology.org/ontology/MESH/C088691 http://purl.bioontology.org/ontology/MESH/C481699 http://purl.bioontology.org/ontology/MESH/C073089 http://purl.bioontology.org/ontology/MESH/C095787
MDA	19741119
MMR	20160531
MN	D02.455.849.291.686 D03.383.129.578.805 D03.132.740
notation	D012433
prefLabel	Ryanodine
TERMUI	T036947
TH	NLM (1975)
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D004224 http://purl.bioontology.org/ontology/MESH/D000470 http://purl.bioontology.org/ontology/MESH/D011758

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/CSP/0093-1309	CRISP	CUI
http://purl.bioontology.org/ontology/MSHFRE/D012433	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNMI/C-32013	SNMI	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/40352008	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SCTSPA/40352008	SCTSPA	CUI
http://purl.bioontology.org/ontology/SNMI/C-30331	SNMI	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000166904	NDFRT	CUI
http://purl.bioontology.org/ontology/CSP/0093-1309	CRISP	CUI
http://purl.bioontology.org/ontology/CSP/0093-1309	CRISP	LOOM
http://purl.obolibrary.org/obo/CHEBI_8925	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_8925	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_8925	BIOMODELS	LOOM
http://stirdf.jst.go.jp/id/200907077632407567	IOBC	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/40352008	SNOMEDCT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.849.291.686	RH-MESH	LOOM
http://purl.obolibrary.org/obo/OMIT_0013338	OMIT	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017059	PMAPP-PMO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D012433	RH-MESH	LOOM
http://purl.bioontology.org/ontology/SNMI/C-30331	SNMI	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.129.578.805	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D012433	BERO	LOOM
http://purl.bioontology.org/ontology/CSP/0093-1309	CRISP	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.740	RH-MESH	LOOM
http://id.nlm.nih.gov/mesh/D012433	MDM	LOOM
http://purl.jp/bio/4/id/200906092939138550	IOBC	LOOM