loading...| Preferred Name |
Angiotensinogen |
|
| Synonyms |
Renin Substrate Tetradecapeptide, Renin Substrate Renin Substrate Tetradecapeptide Hypertensinogen Renin-Substrate Serpin A8 Angiotensinogen (protein renin substrate) Proangiotensin SERPINA8 |
|
| Definitions |
A synthetic or processed 14-amino acid peptide that is used to measure RENIN activities. An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver in response to lowered blood pressure and secreted into blood circulation. Angiotensinogen is the inactive precursor of the ANGIOTENSINS produced in the body by successive enzyme cleavages. Cleavage of angiotensinogen by RENIN yields the decapeptide ANGIOTENSIN I. Further cleavage of angiotensin I (by ANGIOTENSIN CONVERTING ENZYME) yields the potent vasoconstrictor octapeptide ANGIOTENSIN II; and then, via other enzymes, other angiotensins also involved in the hemodynamic-regulating RENIN-ANGIOTENSIN SYSTEM. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000808 |
|
| altLabel |
Renin Substrate Tetradecapeptide, Renin Substrate Renin Substrate Tetradecapeptide Hypertensinogen Renin-Substrate Serpin A8 Angiotensinogen (protein renin substrate) Proangiotensin SERPINA8 |
|
| AQL |
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
| cui |
C0003017 C0086906 |
|
| DC |
1 |
|
| definition |
A synthetic or processed 14-amino acid peptide that is used to measure RENIN activities. An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver in response to lowered blood pressure and secreted into blood circulation. Angiotensinogen is the inactive precursor of the ANGIOTENSINS produced in the body by successive enzyme cleavages. Cleavage of angiotensinogen by RENIN yields the decapeptide ANGIOTENSIN I. Further cleavage of angiotensin I (by ANGIOTENSIN CONVERTING ENZYME) yields the potent vasoconstrictor octapeptide ANGIOTENSIN II; and then, via other enzymes, other angiotensins also involved in the hemodynamic-regulating RENIN-ANGIOTENSIN SYSTEM. |
|
| DX |
19870101 |
|
| HN |
87(75); was see under ANGIOTENSINS 1975-86 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
11002-13-4 0 |
|
| isa | ||
| Machine permutation |
87; was see under ANGIOTENSINS 1975-86 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C000610416 http://purl.bioontology.org/ontology/MESH/C079544 http://purl.bioontology.org/ontology/MESH/C515557 http://purl.bioontology.org/ontology/MESH/C045142 http://purl.bioontology.org/ontology/MESH/C039583 http://purl.bioontology.org/ontology/MESH/C055796 http://purl.bioontology.org/ontology/MESH/C534933 |
|
| MDA |
19741119 |
|
| MMR |
20200609 |
|
| MN |
D12.776.872.020 D12.776.811.070 D12.644.456.073.070 D12.644.861.020 |
|
| notation |
D000808 |
|
| PA |
D015842 |
|
| prefLabel |
Angiotensinogen |
|
| TERMUI |
T002408 T002407 T002405 T734759 T001079484 T002406 T002404 |
|
| TH |
NLM (1975) UNK (19XX) NLM (2021) NLM (2010) |
|
| tui |
T116 T123 |
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D011498 |