loading...| Preferred Name |
Trabectedin |
|
| Synonyms |
ET743 |
|
| Definitions |
A complex structure that includes isoquinolines joined by a cyclic ester; it is a DNA-binding agent and guanine N2 alkylator derived from the marine tunicate, Ecteinascidia turbinata. Trabectedin is used for the treatment of advanced soft-tissue SARCOMA, after failure of ANTHRACYCLINES or IFOSFAMIDE drug therapy. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000077606 |
|
| altLabel |
ET743 Yondelis Ecteinascidin 743 ET 743 ET-743 NSC 684766 |
|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C1311071 C0388976 C1311070 C1312408 |
|
| DC |
1 |
|
| definition |
A complex structure that includes isoquinolines joined by a cyclic ester; it is a DNA-binding agent and guanine N2 alkylator derived from the marine tunicate, Ecteinascidia turbinata. Trabectedin is used for the treatment of advanced soft-tissue SARCOMA, after failure of ANTHRACYCLINES or IFOSFAMIDE drug therapy. |
|
| DX |
20190101 |
|
| HN |
2019 (1996) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
ID0YZQ2TCP 0 |
|
| isa | ||
| LT |
TRD |
|
| Machine permutation |
2019; TRABECTIDIN was indexed under DIOXOLES and TETRAHYDROISOQUINOLINES 2007-2018; and under ISOQUINOLINES 1996-2018 |
|
| MDA |
20180709 |
|
| MMR |
20180409 |
|
| MN |
D03.383.246.619 D03.633.100.531.820.781 |
|
| notation |
D000077606 |
|
| PA |
D018906 |
|
| prefLabel |
Trabectedin |
|
| RR |
114899-77-3 (Trabectedin) |
|
| TERMUI |
T000940463 T290325 T554006 T548934 T290324 T000940461 |
|
| TH |
NLM (1996) FDA SRS (2017) USAN (2003) INN (19XX) NLM (2003) |
|
| tui |
T109 T121 |
|
| subClassOf |