Medical Subject Headings

Last uploaded: August 28, 2024
Preferred Name

Eplerenone
Synonyms

9,11-Epoxy-7-(methoxycarbonyl)-3-oxo-17-pregn-4-ene-21,17-carbolactone

Eplerenon

Inspra

Spiro(cyclopenta(7,8)phenanthro(4b,5-b)oxirene-7(3H),2'(3'H)-furan)-10-carboxylic acid, 2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-4a,6a-dimethyl-2,5'-dioxo-, methyl ester, (4aS,4bR,5aR,6aS,7 R,9aS,9bR,10R)-

Definitions

A spironolactone derivative and selective ALDOSTERONE RECEPTOR antagonist that is used in the management of HYPERTENSION and CONGESTIVE HEART FAILURE, post-MYOCARDIAL INFARCTION.

ID

http://purl.bioontology.org/ontology/MESH/D000077545

altLabel

9,11-Epoxy-7-(methoxycarbonyl)-3-oxo-17-pregn-4-ene-21,17-carbolactone

Eplerenon

Inspra

Spiro(cyclopenta(7,8)phenanthro(4b,5-b)oxirene-7(3H),2'(3'H)-furan)-10-carboxylic acid, 2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-4a,6a-dimethyl-2,5'-dioxo-, methyl ester, (4aS,4bR,5aR,6aS,7 R,9aS,9bR,10R)-

AQL

AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR

cui

C1144054

C0961485

DC

1

definition

A spironolactone derivative and selective ALDOSTERONE RECEPTOR antagonist that is used in the management of HYPERTENSION and CONGESTIVE HEART FAILURE, post-MYOCARDIAL INFARCTION.

DX

20190101

HN

2019 (2000)

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000031

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000819

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000528

Inverse of RB

0

6995V82D0B

isa

http://purl.bioontology.org/ontology/MESH/D000959

http://purl.bioontology.org/ontology/MESH/D000451

LT

TRD

Machine permutation

2019; EPLERENONE was indexed under SPIRONOLACTONE/analogs&derivatives 2000-2018

MDA

20180709

MMR

20180409

MN

D02.540.383

D04.210.500.745.745.329

notation

D000077545

PA

D000959

D000451

prefLabel

Eplerenone

TERMUI

T000940100

T522479

T000940099

T000940102

TH

US

NLM (2009)

NLM (2000)

FDA SRS (2014)

USAN (19XX)

INN (19XX)

NLM (2010)

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/MESH/D011283

http://purl.bioontology.org/ontology/MESH/D007783

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Mapping To Ontology Source
http://purl.bioontology.org/ontology/RXNORM/342280 RXNORM CUI
http://purl.bioontology.org/ontology/NDFRT/N0000010111 NDFRT CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000741940 PDQ CUI
http://purl.bioontology.org/ontology/ATC/C03DA04 ATC CUI
http://purl.bioontology.org/ontology/SNOMEDCT/407010008 SNOMEDCT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148782 NDFRT CUI
http://purl.bioontology.org/ontology/MSHFRE/D000077545 MSHFRE CUI
http://purl.bioontology.org/ontology/SCTSPA/398699008 SCTSPA CUI
http://purl.bioontology.org/ontology/SNOMEDCT/398699008 SNOMEDCT CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000741940 PDQ CUI
http://purl.bioontology.org/ontology/RXNORM/298869 RXNORM CUI
http://purl.bioontology.org/ontology/NDDF/009774 NDDF CUI
http://purl.bioontology.org/ontology/SCTSPA/407010008 SCTSPA CUI
http://purl.bioontology.org/ontology/VANDF/4021363 VANDF CUI
http://purl.obolibrary.org/obo/CHEBI_31547 DRON LOOM
http://www.drugbank.ca/drugs/DB00700 FTC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0961485 OCHV LOOM
https://go.drugbank.com/drugs/DB00700 MDM LOOM
http://purl.bioontology.org/ontology/ATC/C03DA04 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/407010008 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#53572 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_31547 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_31547 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_31547 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_31547 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_31547 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_31547 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_31547 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_31547 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_31547 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_31547 NIFSTD LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148782 NDFRT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025559 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/XCO_0000840 XCO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47513 NCIT LOOM
http://purl.jp/bio/4/id/200906033235388997 IOBC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000741940 PDQ LOOM
http://purl.bioontology.org/ontology/RXNORM/298869 RXNORM LOOM
http://purl.bioontology.org/ontology/NDDF/009774 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C414690 RH-MESH LOOM
http://bmi.utah.edu/ontologies/hfontology/C0961485 HFO LOOM
http://stirdf.jst.go.jp/id/200907064409953911 IOBC LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02118 MIO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02118 MIO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02118 MIO LOOM
http://purl.bioontology.org/ontology/VANDF/4021363 VANDF LOOM
http://purl.obolibrary.org/obo/NCIT_C47513 BERO LOOM