loading...| Preferred Name |
Troglitazone |
|
| Synonyms |
5-(4-((6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl)-2,4-thiazolidinedione) - T |
|
| Definitions |
A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000077288 |
|
| altLabel |
5-(4-((6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl)-2,4-thiazolidinedione) - T Prelay 2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)- CS 045 CS-045 Rezulin CS045 |
|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C1097080 C0056565 C0245514 C0701265 |
|
| DC |
1 |
|
| definition |
A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity. |
|
| DX |
20190101 |
|
| HN |
2019 (1988) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
I66ZZ0ZN0E 0 |
|
| isa | ||
| LT |
TRD |
|
| Machine permutation |
2019; TROGLITAZONE was indexed under CHROMANS and THIAZOLIDINEDIONES 2004-2018; and under THIAZOLES 1988-2003 |
|
| Mapped from | ||
| MDA |
20180709 |
|
| MMR |
20180227 |
|
| MN |
D03.633.100.150.240.612 D02.886.675.933.750 D03.383.663.283.240.612 D03.383.129.708.933.750 |
|
| notation |
D000077288 |
|
| PA |
D007004 |
|
| prefLabel |
Troglitazone |
|
| RR |
97322-87-7 (Troglitazone) |
|
| TERMUI |
T191292 T462343 T191293 T191294 T000938775 T000938776 |
|
| TH |
US MX NLM (2001) USAN (1994) INN (19XX) FDA SRS (2015) NLM (1988) |
|
| tui |
T109 T121 |
|
| subClassOf |