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Last uploaded:
August 28, 2024
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| Preferred Name | venetoclax | |
| Synonyms |
4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro-2H-pyran-4-ylmethyl)amino)phenyl)sulfonyl)-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzamide RG-7601 Venclexta benzamide, 4-(4-((2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-n-((3-nitro-4-(((tetrahydro-2h-pyran-4-yl)methyl)amino)phenyl)sulfonyl)-2-(1h-pyrrolo(2,3-b)pyridin-5-yloxy)- GDC-0199 ABT-199 RG7601 |
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| ID |
http://purl.bioontology.org/ontology/MESH/C579720 |
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| altLabel |
4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro-2H-pyran-4-ylmethyl)amino)phenyl)sulfonyl)-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzamide RG-7601 Venclexta benzamide, 4-(4-((2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-n-((3-nitro-4-(((tetrahydro-2h-pyran-4-yl)methyl)amino)phenyl)sulfonyl)-2-(1h-pyrrolo(2,3-b)pyridin-5-yloxy)- GDC-0199 ABT-199 RG7601
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| cui |
C3641087 C4079830 C4224858 C3641088 C4282411
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| HM |
D019086 D013449
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| Inverse of RB |
N54AIC43PW
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| isa | ||
| LT |
TRD
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| Mapped to | ||
| MDA |
20130414
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| MeSH Frequency |
1222
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| MMR |
20161006
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| notation |
C579720
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| PA |
D000970
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| prefLabel |
venetoclax
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| SC |
1
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| Scope Statement |
A BCL-2 inhibitor with antineoplastic activity that is used in the treatment of CHRONIC LYMPHOCYTIC LEUKEMIA associated with chromosome 17p deletion; structure in first source.
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| SRC |
Nat Med. 2013 Feb;19(2):202-8.
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| TERMUI |
T840428 T000908598 T840429 T000895293 T000908854 T000908594 T000908596 T000908597
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| TH |
NLM (2016) USAN (19XX) INN (19XX) NLM (2013) NLM (2017)
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| tui |
T109 T121
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