loading...| Preferred Name |
ximelagatran |
|
| Synonyms |
xi-melagatran H 376 95 Exanta H 376-95 glycine, N-((1R)1-cyclohexyl-2-((2S)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester glycine, N-((1)1-cyclohexyl-2-((2)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester |
|
| ID |
http://purl.bioontology.org/ontology/MESH/C426686 |
|
| altLabel |
xi-melagatran H 376 95 Exanta H 376-95 glycine, N-((1R)1-cyclohexyl-2-((2S)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester glycine, N-((1)1-cyclohexyl-2-((2)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester |
|
| cui |
C1314929 C0966370 C1174793 |
|
| HM |
D001596 D001384 |
|
| Inverse of RB |
49HFB70472 |
|
| isa | ||
| LT |
TRD |
|
| Mapped to | ||
| MDA |
20010529 |
|
| MeSH Frequency |
388 |
|
| MMR |
20121105 |
|
| notation |
C426686 |
|
| PA |
D000991 |
|
| prefLabel |
ximelagatran |
|
| SC |
1 |
|
| Scope Statement |
prodrug (via hydroxylation) of melagatran & a direct thrombin inhibitor; liver toxicity concerns so AZD0837 being developed to replace this |
|
| SRC |
Thromb Res 2001 Feb 1;101(3):171-81 |
|
| TERMUI |
T448200 T666337 T472630 T535069 T448198 T448199 T448201 |
|
| TH |
FDA SRS (2013) NLM (2001) USAN (19XX) INN (19XX) NLM (2003) NLM (2006) |
|
| tui |
T109 T121 |