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Medical Dictionary for Regulatory Activities Terminology (MedDRA)
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MEDDRA/20000020
http://purl.bioontology.org/ontology/MEDDRA/20000020
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| Preferred Name | Severe cutaneous adverse reactions (SMQ) |
| Definitions |
This SMQ was developed to identify cases of severe, sometimes life-threatening skin reactions that are often drug-induced. Severe cutaneous adverse reactions (SCARs) include: Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, and acute generalized exanthematous pustulosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | This SMQ was developed to identify cases of severe, sometimes life-threatening skin reactions that are often drug-induced. Severe cutaneous adverse reactions (SCARs) include: Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, and acute generalized exanthematous pustulosis. |
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| prefLabel | Severe cutaneous adverse reactions (SMQ)
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| SMQ STATUS | A
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| type | |
| tui | T185
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| notation | 20000020
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| SMQ LEVEL | 1
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| Semantic type UMLS property | |
| SMQ ALGO | N
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| cui | C1869024
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| SMQ SOURCE | Roujeau JC and Stern RS. Severe adverse cutaneous reactions to drugs. New England Journal of Medicine 1994; 331: 1272-1285. Reporting Adverse Drug Reactions. Definitions of terms and criteria for their use. CIOMS publication, Geneva 1999. RegiSCAR group (http://regiscar.uni-freiburg.de). Severe Cutaneous Adverse Reactions to Drugs (SCAR): Definitions, Diagnostic Criteria, Genetic Predisposition, Jean-Claude Roujeau, Laurence Allanore, Yvonne Liss, Maja Mockenhaupt (http://www.dermatol-sinica.com/web/data/20091130043801.pdf)
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