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Microbial Conditions Ontology
Preferred Name | paromomycin | |
Synonyms |
UOZODPSAJZTQNH-LSWIJEOBSA-N R-400 Zygomycin A1 paromomycinum R 400 paucimycinum estomycin crestomycin (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside Monomycin A 615.62850 NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O paucimycin Neomycin E Catenulin paromomicina paromomycin hydroxymycin InChI=1S/C23H45N5O14/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22/h5-23,29-36H,1-4,24-28H2/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1 C23H45N5O14 paromomycine Paromomycin I Aminosidin 0 neomycin E 615.296 Hydroxymycin aminosidine PAROMOMYCIN Paromomycin |
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Definitions |
An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. |
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ID |
http://purl.obolibrary.org/obo/CHEBI_7934 |
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database_cross_reference |
colombos:PAROMOMYCIN colombos:PAROMOMYCIN:+UNKNOWN Patent:US2895876 KEGG:D07467 PMID:8036682 Drug_Central:2067 CAS:7542-37-2 PMID:18447603 KEGG:C00832 PDBeChem:PAR Reaxys:72285 DrugBank:DB01421 Patent:US2916485 PMID:18947845
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has exact synonym |
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside PAROMOMYCIN Paromomycin
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has functional parent | ||
has role |
http://purl.obolibrary.org/obo/CHEBI_35820 |
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has_alternative_id |
CHEBI:44703
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has_obo_namespace |
chebi_ontology
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has_related_synonym |
UOZODPSAJZTQNH-LSWIJEOBSA-N R-400 Zygomycin A1 paromomycinum R 400 paucimycinum estomycin crestomycin (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside Monomycin A 615.62850 NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O paucimycin Neomycin E Catenulin paromomicina paromomycin hydroxymycin InChI=1S/C23H45N5O14/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22/h5-23,29-36H,1-4,24-28H2/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1 C23H45N5O14 paromomycine Paromomycin I Aminosidin 0 neomycin E 615.296 Hydroxymycin aminosidine
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id |
CHEBI:7934
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in_subset | ||
label |
paromomycin
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notation |
CHEBI:7934
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prefLabel |
paromomycin
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textual definition |
An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis.
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subClassOf |
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