loading...| Preferred Name |
AL amyloidosis |
|
| Synonyms |
amyloidosis primary systemic primary AL amyloidosis primary systemic AL amyloidosis systemic AL amyloidsis amyloidosis AL primary systemic amyloidosis Light chain amyloidosis primary amyloidosis (formerly) Light-chain amyloidosis primary amyloidosis |
|
| Definitions |
AL Amyloidosis is a plasma cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains usually produced by a plasma cell tumor. It usually presents as primary systemic amyloidosis (PSA) with multiple organ involvement and less frequently as primary localized amyloidosis (PLA) restricted to a single organ. |
|
| ID |
http://purl.obolibrary.org/obo/MONDO_0019438 |
|
| database_cross_reference |
MedDRA:10036673 UMLS:C0268381 ICD10:E85.9 MESH:C531616 GARD:0005797 Orphanet:85443 |
|
| exactMatch |
http://www.orpha.net/ORDO/Orphanet_85443 http://identifiers.org/meddra/10036673 |
|
| has exact synonym |
Light-chain amyloidosis primary amyloidosis |
|
| has related synonym |
amyloidosis primary systemic primary AL amyloidosis primary systemic AL amyloidosis systemic AL amyloidsis amyloidosis AL primary systemic amyloidosis Light chain amyloidosis primary amyloidosis (formerly) |
|
| id |
MONDO:0019438 |
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| imported from | ||
| in_subset | ||
| label |
AL amyloidosis |
|
| notation |
MONDO:0019438 |
|
| prefLabel |
AL amyloidosis |
|
| textual definition |
AL Amyloidosis is a plasma cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains usually produced by a plasma cell tumor. It usually presents as primary systemic amyloidosis (PSA) with multiple organ involvement and less frequently as primary localized amyloidosis (PLA) restricted to a single organ. |
|
| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0016330 http://purl.obolibrary.org/obo/MONDO_0016345 http://purl.obolibrary.org/obo/MONDO_0019724 http://purl.obolibrary.org/obo/MONDO_0019065 |