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Integrated Ontology for Symptom Phenotype Terminologies
Last uploaded:
January 10, 2023
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Preferred Name | Spasticity, muscle | |
Synonyms |
Clasp-Knife Spasticity 肌肉抽搐 muscle twitching Spasticity, Clasp-Knife Clasp Knife Spasticity Muscle Spasticity Spasticity, Muscle Clasp-knife spasticity Spastic |
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ID |
http://www.tcmkg.com/ISPO/ISPO_00001971 |
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database_cross_reference |
SYMP:0000394 MeSH:D009128 UMLS:C0277820
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definition |
A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a \"free interval\") followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54) Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations may be visualized as a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. They may represent a benign condition or occur as a manifestation of MOTOR NEURON DISEASE or PERIPHERAL NERVOUS SYSTEM DISEASES. (Adams et al., Principles of Neurology, 6th ed, p1294)
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has_exact_synonym |
Clasp-Knife Spasticity 肌肉抽搐 muscle twitching Spasticity, Clasp-Knife Clasp Knife Spasticity Muscle Spasticity Spasticity, Muscle Clasp-knife spasticity Spastic
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has_obo_namespace |
symptoms
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id |
ISPO:00001971
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label |
Spasticity, muscle
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notation |
ISPO:00001971
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prefLabel |
Spasticity, muscle
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subClassOf |
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Mapping To | Ontology | Source |
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http://purl.bioontology.org/ontology/MEDDRA/10041418 | MEDDRA | LOOM |