loading...| Preferred Name | Loperamide | |
| Synonyms |
CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 loperamida loperamidum InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3 InChIKey=RDOIQAHITMMDAJ-UHFFFAOYSA-N C29H33ClN2O2 loperamide 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide Loperamide |
|
| Definitions |
A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_6532 |
|
| charge |
0 |
|
| chemical effective in vitro against virus | ||
| chemical has protein target |
http://purl.obolibrary.org/obo/PR_P01189 http://purl.obolibrary.org/obo/PR_P0DP23 http://purl.obolibrary.org/obo/PR_O00555 http://purl.obolibrary.org/obo/PR_P41145 |
|
| chemical has protein target as agonist |
http://purl.obolibrary.org/obo/PR_P41145 |
|
| chemical has protein target as inhibitor | ||
| database_cross_reference |
CAS:53179-11-6 HMDB:HMDB0004999 Wikipedia:Loperamide LINCS:LSM-3365 KEGG:D08144 ChemIDplus:53179-11-6 KEGG COMPOUND:53179-11-6 KEGG:C07080 Patent:FR2100711 PMID:15900907 DrugBank:DB00836 PMID:19034106 KEGG COMPOUND:C07080 Drug_Central:1599 Beilstein:1558273 Patent:US3714159 PMID:24398461 Reaxys:1558273 |
|
| definition |
A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease. |
|
| definition source |
PMID: 30918074; PMID: 27344959; PMID: 32366720 |
|
| formula |
C29H33ClN2O2 |
|
| has exact synonym |
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide Loperamide loperamide |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_149553 |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 loperamida loperamidum InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3 InChIKey=RDOIQAHITMMDAJ-UHFFFAOYSA-N C29H33ClN2O2 loperamide |
|
| has_RxCUI |
6468 |
|
| id |
CHEBI:6532 |
|
| imported from | ||
| in_subset | ||
| inchi |
InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3 |
|
| inchikey |
RDOIQAHITMMDAJ-UHFFFAOYSA-N |
|
| is bearer of | ||
| is conjugate base of | ||
| label |
Loperamide loperamide |
|
| mass |
477.03800 |
|
| monoisotopicmass |
476.22306 |
|
| notation |
CHEBI:6532 |
|
| prefLabel |
Loperamide |
|
| smiles |
CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_83403 http://purl.obolibrary.org/obo/CHEBI_29347 |