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Human Physiology Simulation Ontology
Last uploaded:
April 7, 2014
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| Preferred Name | lamivudine | |
| Synonyms |
3TC |
|
| Definitions |
Lamivudine (2',3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir, and Epivir-HBV. Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus (YMDD) mutant. Despite this, lamivudine is still used widely as it is well tolerated. source: http://en.wikipedia.org/wiki/Lamivudine |
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| ID |
http://scai.fraunhofer.de/HuPSON#SCAIVPH_00001120 |
|
| definition |
Lamivudine (2',3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).
It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir, and Epivir-HBV.
Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus (YMDD) mutant. Despite this, lamivudine is still used widely as it is well tolerated.
source: http://en.wikipedia.org/wiki/Lamivudine
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|
| exact_synonym |
3TC
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|
| label |
lamivudine
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| prefixIRI |
hupson:SCAIVPH_00001120
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|
| prefLabel |
lamivudine
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| subClassOf |
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